Search results for "Pediatric dermatology"

showing 3 items of 3 documents

Clinical efficacy of blue light full body irradiation as treatment option for severe atopic dermatitis.

2011

Background Therapy of atopic dermatitis (AD) relies on immunosuppression and/or UV irradiation. Here, we assessed clinical efficacy and histopathological alterations induced by blue light-treatment of AD within an observational, non-interventional study. Methodology/Principal Findings 36 patients with severe, chronic AD resisting long term disease control with local corticosteroids were included. Treatment consisted of one cycle of 5 consecutive blue light-irradiations (28.9 J/cm2). Patients were instructed to ask for treatment upon disease exacerbation despite interval therapy with topical corticosteroids. The majority of patients noted first improvements after 2–3 cycles. The EASI score w…

MaleSkin PhysiologyAnatomy and PhysiologyLightmedicine.medical_treatmentlcsh:MedicinePediatric DermatologyAntigen Processing and RecognitionAtopic DermatitisDiseasePediatricsQuality of lifeYoung adultlcsh:ScienceSkinMultidisciplinarymedicine.diagnostic_testT CellsAllergy and HypersensitivityPhysicsElectromagnetic RadiationPhotodermatology and Skin AgingImmunosuppressionAtopic dermatitisMiddle Agedmedicine.anatomical_structureTreatment OutcomePatient SatisfactionObservational StudiesMedicineFemaleWhole-Body IrradiationResearch ArticleAdultmedicine.medical_specialtyLangerhans cellClinical Research DesignImmune CellsImmunologyColorDermatologyDermatitis AtopicYoung AdultUltraviolet RadiationBiopsymedicineHumansSerologic TestsBiologybusiness.industrylcsh:Rmedicine.diseaseDermatologyClinical trialImmune SystemChronic DiseaseQuality of Lifelcsh:QClinical ImmunologybusinessPloS one
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Cerebriform sebaceous nevus: a subtype of organoid nevus due to specific postzygotic FGFR2 mutations.

2021

Background Postzygotic mutations in FGFR2 have been identified in mosaic forms of acne, keratinocytic epidermal nevi, nevoid acanthosis nigricans / rounded and velvety epidermal nevus and in two fetuses with papillomatous pedunculated sebaceous nevus (PPSN). Objectives To determine the clinical and genetic characteristics of children with cerebriform, papillomatous, and pedunculated variants of sebaceous nevi. Methods Infants diagnosed with sebaceous nevi characterized by a cerebriform, papillomatous, and/or pedunculated morphology over a 10-year period (2010 - 2019) at three pediatric dermatology centers in Switzerland and France were included in this case series. Clinical and histological…

medicine.medical_specialtySkin NeoplasmsCutis gyrataDermatologyEpidermal nevusmedicine.disease_causeGermline030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicinemedicineNevusHumansPediatric dermatologyReceptor Fibroblast Growth Factor Type 2skin and connective tissue diseasesAcanthosis nigricansNevusMutationintegumentary systembusiness.industryOrganoid Nevusmedicine.diseaseDermatologyOrganoidsInfectious Diseases030220 oncology & carcinogenesisMutationbusinessJournal of the European Academy of Dermatology and Venereology : JEADVReferences
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Management of chronic urticaria in children: a clinical guideline

2019

Abstract The aim of this guidance is to provide recommendations to clinicians and other interested parties on chronic urticaria in children. The Italian Society for Pediatrics (SIP), the Italian Society for Allergy and Immunology (SIAIP), the Italian Society for Pediatric dermatology (SIDerP) convened a multidisciplinary panel that prepared clinical guidelines for diagnosis and management of chronic urticaria in childhood. Key questions on epidemiology, natural history, diagnosis, and management were developed. The literature was systematically searched and evaluated, recommendations were rated and algorithms for diagnosis and treatment were developed. The recommendations focus on identific…

medicine.medical_specialtyUrticariaAllergyReviewPathogenesisOmalizumabOmalizumab03 medical and health sciences0302 clinical medicinePathogenesiMultidisciplinary approach030225 pediatricsEpidemiologymedicineHumans030212 general & internal medicineAngioedemaPediatric dermatologyChildChildrenChronic urticariaPediatricAngioedemabusiness.industrylcsh:RJ1-570lcsh:PediatricsGeneral MedicineGuidelineChronic urticariaChronic spontaneous urticariaSettore MED/38ManagementNatural historyInducible uricariaItalyFamily medicineTherapymedicine.symptombusinessmedicine.drugItalian Journal of Pediatrics
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